Biotin and derivatives
eMolecules 1807518-72-4 | Mal-PEG1-NHS ester | Ambeed | MFCD26127783 | 310.262 | C13H14N2O7 | 97.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 5g | 794508519
Mal-PEG1-NHS ester | Ambeed | 1807518-72-4 | MFCD26127783 | 310.262 | C13H14N2O7 | 97.000 | O=C(CCOCCN1C(=O)C=CC1=O)ON1C(=O)CCC1=O | 5g | 794508519
Medchemexpress LLC m-PEG11-NHS ester | 3119903-67-9 | C28H51NO15 | 100 MG
m-PEG11-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is recommended for storage at -20°C, sealed, and away from moisture and light. If in solvent, it can be stored at -80°C for 6 months or -20°C for 1 month, also with sealed storage, away from moisture and light.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Store at -20°C, sealed, away from moisture and light
- Extended storage in solvent possible at -80°C
![eMolecules 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 25g | 490500208](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000471012.jpg-250.jpg)
eMolecules 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 25g | 490500208
Biotin | Ambeed | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 25g | 490500208
Medchemexpress LLC Pentanediamide, N1-[4-[[4-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo... | 1599432-18-4 | MFCD30496724 | 99.7% | 1097.37 g/mol | C56H80N12O9S | 50 MG
Ibrutinib-biotin is a biotin-conjugated chemical probe derived from the BTK inhibitor ibrutinib. It features ibrutinib linked to biotin via a long-chain linker and is designed for target engagement, affinity pull-downs, and assay development directed at Bruton's tyrosine kinase (BTK).
- Biotin-conjugated probe for affinity capture and pull-down assays.
- Derived from a BTK inhibitor for target-specific engagement.
- Low-nanomolar potency against BTK (IC50 0.755-1.02 nM).
- High purity suitable for research applications (>99.6%).
- Available as solid material and as a 10 mM solution in DMSO.
- Molecular weight approximately 1,097.37 g/mol.
Medchemexpress LLC Biotin-PEG1-azide | 1204085-48-2 | 99.9% | 356.44 g/mol | C14H24N6O3S | 50 MG
Biotin-PEG1-azide is a biotinylated polyethylene glycol (PEG1) azide reagent used as a linker and click-chemistry handle for conjugation, labeling, and affinity-based capture in research applications.
- introduces a biotin tag and an azide functional group for covalent conjugation
- suitable for copper-catalyzed and strain-promoted azide-alkyne cycloaddition
- high purity for reliable experimental results
- available in small-scale quantities suitable for synthesis and labeling workflows
- storage recommended at low temperatures to preserve stability
eMolecules 58-85-5 | D-(+)-Biotin | Apollo Scientific | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 1g | 562432212
D-(+)-Biotin | Apollo Scientific | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 1g | 562432212
![eMolecules 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 10g | 518521733](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000169626.jpg-250.jpg)
eMolecules 58-85-5 | Biotin | Ambeed | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 10g | 518521733
Biotin | Ambeed | 58-85-5 | MFCD00005541 | 244.310 | C10H16N2O3S | 98.000 | OC(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@H]12 | 10g | 518521733
Medchemexpress LLC DBCO-NHCO-S-S-NHS ester | 96.0% | 565.66 | C28H27N3O6S2 | 25 MG
DBCO-NHCO-S-S-NHS ester is a cleavable antibody-drug conjugate (ADC) linker and click-chemistry reagent containing a DBCO moiety. It is designed to couple to amines via the NHS ester and to react with azide-bearing molecules through strain-promoted alkyne-azide cycloaddition (SPAAC); the disulfide (S-S) bond provides a reducible, cleavable linker for payload release.
- cleavable disulfide linker for reductive release
- n-hydroxysuccinimide (nhs) ester for amine coupling
- dbco group enables copper-free spaac click chemistry with azides
- solid, white to off-white appearance for easy handling
- available in small research pack sizes (including 25 mg)
- storage: powder at -20°C; in solvent stability at -80°C (6 months) or -20°C (1 month)
Medchemexpress LLC 3-Pyrrolidinesulfonic acid, 1-(acetyloxy)-2,5-dioxo- | 152305-87-8 | 98.0% | C6H7NO7S | 25 MG
Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs are compounds containing two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. PROTACs function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl chain-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Targets an E3 ubiquitin ligase
- Targets a specific protein
- Exploits intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
- Relevant to cancer research
- Relevant to cancer targeted therapy
- Classified as a PROTAC linker
- Functions as an inhibitor
Medchemexpress LLC Propanoic acid, 3-(2-azidoethoxy)-, 2,5-dioxo-1-pyrrolidinyl ester | 1807530-06-8 | 99.8% | C9H12N4O5 | 50 MG
Azido-PEG1-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. It can also engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an azide group
- Facilitates copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc)
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Suitable for use with molecules containing alkyne, DBCO, or BCN groups
- Enables selective degradation of target proteins
Medchemexpress LLC DBCO-NHS ester | 1353016-71-3 | 99.5% | 402.40 | C23H18N2O5 | 10 MG
DBCO-NHS ester is a dibenzocyclooctyne N-hydroxysuccinimidyl ester used as a click-chemistry linker to enable strain-promoted alkyne-azide cycloaddition (SPAAC) for bioconjugation and antibody-drug conjugate synthesis. Supplied as a powder with recommended storage and handling guidance; suitable for laboratory research applications.
- Click-chemistry reagent for strain-promoted alkyne-azide cycloaddition (SPAAC).
- High purity (≈99.5% by LCMS).
- Molecular weight 402.40, chemical formula C23H18N2O5.
- Available in small-mg packages for research use.
- Store as powder at -20°C; follow SDS for solution storage and handling.
Apexbio Technology LLC NHS-SS-11-Biotin(Synonyms: Sulfo-NHS-SS-Biotin, EZ-Link NHS-SS-Biotin, NHS-SS-D-Biotin, N-Hydroxysuccinimidyl-SS-Biotin), 50mg, CAS: 142439-92-7.
NHS-SS-11-Biotin (CAS 142439-92-7) is an amine-reactive biotinylation reagent commonly used in biochemical research Structurally it possesses an N-hydroxysuccinimide (NHS) ester group that covalently reacts with primary amines of target proteins or biomolecules forming stable amide bonds and releasing sulfo-NHS This reagent features a cleavable disulfide linker and an extended spacer arm of approximately 24 3 enhancing probe accessibility to avidin or streptavidin conjugates It is utilized extensively for reversible biotinylation affinity purification or labeling studies in proteomics and cell biology applications
Apexbio Technology LLC Sulfo-NHS-LC-D-Desthiobiotin 5X1mg
Sulfo-NHS-LC-D-Desthiobiotin is a sulfonated amine-reactive labeling reagent targeting primary amines on proteins or peptides It is designed to covalently label cell-surface proteins by reacting with lysine residues or protein N-termini thereby enabling selective modification of these proteins Sulfo-NHS-LC-D-Desthiobiotin exerts its biological activity primarily through covalent reaction with primary amines via its activated Sulfo-NHS ester Due to its membrane-impermeable negatively charged sulfonate group it selectively labels cell-surface proteins without entering intact cells Based on these chemical properties Sulfo-NHS-LC-D-Desthiobiotin holds research potential in affinity purification biotin-streptavidin interaction assays selective enrichment and analytical workflows involving reversible labeling of surface proteins
Apexbio Technology LLC Sulfo-NHS-SS-11-Biotin 1g
Sulfo-NHS-SS-11-Biotin is an amine-reactive water-soluble biotinylation reagent containing an N-hydroxysulfosuccinimide (Sulfo-NHS) active ester group and a cleavable disulfide bond The Sulfo-NHS moiety reacts specifically with primary amines in proteins peptides or other biomolecules forming stable amide linkages This reagent introduces a disulfide-containing spacer arm enabling subsequent selective cleavage under reducing conditions for release of biotinylated molecules It is commonly employed in affinity chromatography immunoprecipitation experiments cell surface protein labeling and target identification allowing isolation purification or detection of biomolecules through streptavidin or avidin affinity interactions
Medchemexpress LLC IL-12 Human Biotin 20ug | 20ug
IL-35 protein plays a key role in immune regulation forming IL-12 cytokine with IL12B or IL-35 cytokine with EBI3/IL27B IL-12 modulates T cell and natural killer cell responses and induces interferon gamma production IL-12 Protein Human (Biotinylated HEK293 His-Avi) is a recombinant protein dimer complex containing human-derived IL-12 protein expressed by HEK293 with C-Avi C-His labeled tag IL-12 Protein Human (Biotinylated HEK293 His-Avi) has molecular weight of 40-45 kDa